Team – the yeoman lab

Dr Carl Yeoman – Principal Investigator

yeoman_lab_image-48 copy Carl is an Associate Professor and Director of Montana INBREs Bioinformatics and Biostatistics core at Montana State University. He researches the ecology and evolution of host-associated microbial ecosystems in the context of health, immunological development, and nutrition of host animals.

Google Scholar, Research Gate, LinkedIn.

Phone: (406) 994-7440.

Email: carl.yeoman@montana.edu

Joanna Borgogna – Postdoctoral Research Fellow

Ph.D. Molecular Biosciences (2014 – 2019)

joanna_headshot Joanna earned her Ph.D. in 2019 after working on the interrelationship among the microbiome and metabolome of the human vaginal tract, and their relationship to infection and disease. She is continuing this exciting and cutting edge research as a postdoctoral fellow.

Email: joannalynnborgogna@montana.edu

Jo’s Publications with the Yeoman Lab.

Borgogna JC, Shardell MD, Brotman RM, Yeoman CJ, Ghanem KG, Kadriu H, Ulanov AV, Gaydos CA, Hardick J, Robinson C, Ravel J, Bavoil PM, Tuddenham S. 2020. Vaginal metabolomics profiles: comparing uninfected, C. trachomatis mono- and C. trachomatis/M. genitalium co-infected women. Scientific Reports. 10: 3420 DOI: 10.1038/s41598-020-60179-z

Borgogna JC, Shardell MD, Santori EK, Nelson TM, Rath JM, Glover ED, Ravel J, Gravitt P, Yeoman CJ, Brotman RM. 2020. The vaginal metabolome and microbiota of cervical HPV-positive and HPV-negative women: a cross-sectional analysis. British Journal of Obstetrics & Gynecology. In press. DOI: 10.1111/1471-0528.15981

Nelson TM, Borgogna JC, Michalek, RD, Roberts DW, Rath JM, Glover ED, Ravel J, Shardell MD, Yeoman CJ, Brotman RM. 2018. Cigarette smoking is associated with an altered vaginal tract metabolomic profile. Scientific Reports. 8: 852. PubMed PMID: 29339821; PubMed Central PMCID: PMC5770521; DOI:10.1038/s41598-017-14943-3

Borgogna JC, Yeoman CJ. 2017. The Application of Molecular Methods to Improving Our Understanding of the Vaginal Microbiomes Role in Health and Disease. In: Methods in Microbiology (book chapter). Ed. Colin Harwood. Elsevier. 44: 37 – 91. DOI: 10.1016/bs.mim.2017.08.003

Nelson TM, Borgogna JL, Brotman RM, Ravel J, Walk ST, Yeoman CJ. 2015. Vaginal biogenic amines: Biomarkers of bacterial vaginosis or precursors to vaginal dysbiosis? Front. Physiol. 6:253. DOI: 10.3389/fphys.2015.00253

Savannah Grace – MS Candidate in Animal Sciences

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Savannah is working to isolate bacterial strains from Montana’s wealth of wild ruminant populations capable of degrading the potent toxin Methyllycacontine (MLA) and determine if these bacteria can be introduced to domestic cattle to protect them against larkspur toxicosis.

Herlin (Eri) Kadriu – MS Candidate in Biotechnology

[Picture to come] Eri is working to develop a small intestinal enteroid model for beef cattle and to use this model to explore the influence of gastrointestinal microbes on immune function.

Lab Affiliates

STEPHANIE KEENE – Graduate student (Advisor Mary Miles)

Stephanie is an M.S. candidate in the Nutrition Research Laboratory under Dr. Mary Miles. She is investigating the acute effects of endurance exercise on the levels of endotoxin and other inflammatory markers in athletes.

Lab Alumni

Dr Tiffanie Nelson – NIH Postdoctoral Research Fellow (2014 – 2016)

Tiff is currently a Associate Research Fellow at the Geelong Center for Emerging Infectious Diseases. Keep up with Tiff’s research at Research Gate, Google Citations, and LinkedIn. Tiff can also be contacted at tiffanie.nelson@gmail.com

Tiff’s Publications with the Yeoman Lab.

Nelson TM, Borgogna JC, Michalek, RD, Roberts DW, Rath JM, Glover ED, Ravel J, Shardell MD, Yeoman CJ, Brotman RM. 2018. Cigarette smoking is associated with an altered vaginal tract metabolomic profile. Scientific Reports. 8: 85

Dr Suzanne Ishaq – Postdoctoral Research Fellow (2015 – 2017)

Sue is currently an Assistant Professor at U. Maine. Keep up with Sue’s research on her personal and professional web pages and at Research Gate, LinkedIn, and Google Citation. Sue also runs a science BLOG ‘Give Me The Short Version’. Sue can be contacted at sue.ishaq@maine.edu

Sue’s Publications with the Yeoman Lab.

Ishaq SL, Seipel T, Yeoman CJ, Menalled F. 2020. Dryland cropping systems, weed communities, and disease status modulate the effect of climate conditions on wheat soil bacterial communities. mSphere. In press.

Ishaq SL, Seipel T, Yeoman CJ, Menalled FD. 2020. Soil bacterial communities of wheat vary across the growing season and among dryland farming systems. Geoderma. 358: 113989

Ishaq SL, Lachman MM, Wenner BA, Baeza A, Butler M, Gates E, Olivo S, Geddes JB, Hatfield P, Yeoman CJ. 2019. Pelleted-hay alfalfa feed increases sheep wether weight gain and rumen bacterial richness over loose-hay alfalfa feed. PLoS One 14: e0215797. DOI: 10.1371/journal.pone.0215797

Ishaq SL, Page CM, Yeoman CJ, Murphy TW, Van Emon ML, Stewart WC. 2019. Zinc-amino-acid supplementation alters yearling ram rumen bacterial communities but zinc sulfate supplementation does not. Journal of Animal Sciences. 97: 687 – 697. DOI: 10.1093/jas/sky456.

Yeoman CJ, Ishaq SL, Bichi E, Olivo SK, Lowe JL, Aldridge BM. 2018. Biogeographical differences in the influence of maternal microbial sources on the early successional development of the bovine neonatal gastrointestinal tract. Scientific Reports. 8: 3197. DOI:10.1038/s41598-018-21440-8

Ishaq SL, Yeoman CJ, Whitney TR. 2017. Ground redberry juniper and urea in supplements fed to Rambouillet ewe lambs. Part 2: Ewe lamb rumen microbial communities. Journal of Animal Sciences. 95: 4587. doi:10.2527/jas2017.1731

Perea K, Perz K, Olivo SK, Williams A, Lachman M, Ishaq SL, Thomson J, Yeoman CJ. 2017. Feed efficiency phenotypes in lambs involve changes in ruminal, colonic, and small intestine-located microbiota. Journal of Animal Sciences. 95(6):2585-2592. doi: 10.2527/jas.2016.1222

Ishaq SL, Johnson SP, Miller ZJ, Lehnhoff EA, Olivo S, Yeoman CJ, Menalled FD. 2017. Impact of cropping systems, soil inoculum, and plant species identity on soil bacterial community structure. Microbial Ecology 73(2): 417-434. doi: 10.1007/s00248-016-0861-2.

Feng W, Minor D, Liu M, Li J, Ishaq SL, Yeoman CJ, Lei B. 2016. Null mutations of group A Streptococcus orphan kinase RocA: Selection in mouse infection and comparison with CovS mutations in alteration of in vitro and in vivo protease SpeB expression and virulence. Infection and Immunity 85: e00790-16. doi: 10.1128/IAI.00790-16

Dr. Omolola Betiku – Animal Sciences Ph.D. (2013 – 2017)

Omolola Betiku (Lola) was the Yeoman lab’s first Ph.D. Her research sought to determine how diet and environment influence the gut microbiota of rainbow trout. Lola is now an Assistant professor at Florida A&M U. and can be contacted at ocbetiku@gmail.com

Lola’s Publications with the Yeoman Lab.

Betiku OC, Yeoman CJ, Gaylord TG, Duff GC, Hamerly T, Bothner B, Block SS, Sealey WM. 2017. Differences in Amino Acid Catabolism by Gut Microbes with/without Prebiotics Inclusion in GDDY-based Diet Affect Feed Utilization in Rainbow Trout. Aquaculture. In press

Betiku OC, Yeoman CJ, Gaylord TG, Americus B, Olivo S, Duff GC, Sealey W. 2018. Water system is a controlling variable modulating bacterial diversity of gastrointestinal tract and performance in Rainbow trout. PLoS One. 13: e0195967. DOI: doi.org/10.1371/journal.pone.0195967

Dr. Laura Brutscher Microbiology Ph.D. (2013 – 2017)

laura_headshot Laura applied molecular biology-based approaches to identify and investigate the endosymbiotic relationship between the Wheat Stem Sawfly. Laura can be contacted at laura.brutscher2@gmail.com

Laura’s Publication with the Yeoman Lab.

Yeoman CJ, Brutscher LM, Esen Ö, İbaoğlu F, Fowler C, Eren AM, Wanner K, Weaver DK. 2019. Genome-resolved insights into a novel Spiroplasma symbiont of the Wheat Stem Sawfly (Cephus cinctus). PeerJ 7:e7548 DOI: 10.7717/peerj.7548

Technical Staff

Sarah Olivo (2015 – 2017)

Julie Buono Geddes (2015), Laboratory Technician.

Thomas O’Neill (2013 – 2014) , Laboratory Technician.

Undergraduates

Herlin Kadriu (2018 – 2020) INBRE-USP Scholar

Daria Kotov (2018)

Savannah Gray (2018 – 2019)

Deanna Desonn (2017 – 2018)

Dusti East (2017)

Amanda Embleton (2016 – 2017)

Jessica Donahoo (2016 – 2017)

Trent Jones (2016 – 2017)

Elisa Santori (2016 – 2017) INBRE-USP Scholar

Katheryn Parea (Summer 2016), INBRE Fellow

Megan Meyer (2016)

Curtis Fowler (2015-2016), Undergraduate Researcher

Benjamin Americus (2015-2016), Undergraduate Researcher

Amy Baeza (2014)

Kiki Potter-Jacobs (2014 – 2015)

Jessica Eggers (Summer 2014), Bozeman High School Research Intern.

Tasia Hvamstad (Summer 2014), Montana Apprenticeship Program Research Intern.

Raven Warner (Summer 2014), Montana Apprenticeship Program Research Intern

Medora Lachman (2014 – 2017).

Niall Clancy (2014) Undergraduate Intern

Josh Failing (Summer 2013), Montana Apprenticeship Program Research Intern.

Courtney Subatch (Summer 2013), Montana Apprenticeship Program Research Intern.

Kesley Westveer (Spring 2013), Biotechnology Intern.

Jillian Hatfield (Fall 2012), Undergrad Intern.

Emme Troendle, Research Intern.