Team – the yeoman lab

Dr Carl Yeoman – Principal Investigator

yeoman_lab_image-48 copy Carl is a Professor and Head of the Department of Animal & Range Sciences at Montana State University. He researches the ecology and evolution of host-associated microbial ecosystems in the context of health, immunological development, and nutrition of host animals.

Google Scholar, Research Gate, LinkedIn.

Phone: (406) 994-4850.

Email: carl.yeoman@montana.edu

Joanna Borgogna – Postdoctoral Research Fellow

Ph.D. Molecular Biosciences (2014 – 2019); Postdoctoral Fellow (2019 -)

joanna_headshot Joanna earned her Ph.D. in 2019 after working on improving our understanding the relationships among the female urogenital microbiome and metabolome, behavioral habits such as smoking, and gynecological health, with an emphasis on racial and ethnic minorities. She is continuing this exciting and cutting edge research as a postdoctoral fellow through an NIH Maximizing Opportunities for Scientific and Academic Independent Careers, or MOSAIC, Pathway to Independence Award as she transitions to opening her own lab.

Phone: (406) 994-7440.

Email: joannalynnborgogna@montana.edu

Jo’s Publications with the Yeoman Lab.

Borgogna JC, Grace SG, Holm JB, Aviles Zuniga T, Kadriu H, He X, McCoski SR, Ravel J, Brotman RM, Yeoman CJ. 2023. Investigating the impact of condomless vaginal intercourse and lubricant use on the vaginal metabolome: a pre-observational-–post-observational study. Sexually Transmitted Infections. In press. DOI: 10.1136/sextrans-2022-055667

Zhengru L, Long B, Yeoman CJ, Clifton G, Ellington J, Ellington-Lawrence R, Borgogna JC, Star A. 2022. Bacterial vaginosis monitoring with carbon nanotube field-effect transistors. Analytical Chemistry. 94: 3849–3857 DOI: 10.1021/acs.analchem.1c04755

Borgogna JC, Anastario M, Firemoon P, Rink E, Ricker A, Ravel J, Brotman RM, Yeoman CJ. 2021. Vaginal microbiota of American Indian women and associations with measures of psychosocial stress. PLoS One. 16: e0260813 DOI: 10.1371/journal.pone.0260813

Turpin R, Slopen N, Borgogna JC, Yeoman CJ, He X, Miller RS, Klebanoff MA, Ravel J, Brotman RM. 2021. Perceived Stress and Molecular-BV in the NIH Longitudinal Study of Vaginal Flora. American Journal of Epidemiology. 2021: kwab147. DOI: 10.1093/aje/kwab147

Borgogna JC, Shardell MD, Grace SG, Santori EK, Americus B, Li Z, Ulanov AV, Forney LJ, Nelson T, Brotman RM, Ravel J, Yeoman CJ. 2021. Biogenic amines increase the odds of bacterial vaginosis and affect the growth and lactic acid production by vaginal Lactobacillus spp. Applied and Environmental Microbiology. 87: e03068-20. DOI: 10.1128/AEM.03068-20

Borgogna JC, Shardell MD, Brotman RM, Yeoman CJ, Ghanem KG, Kadriu H, Ulanov AV, Gaydos CA, Hardick J, Robinson C, Ravel J, Bavoil PM, Tuddenham S. 2020. Vaginal metabolomics profiles: comparing uninfected, C. trachomatis mono- and C. trachomatis/M. genitalium co-infected women. Scientific Reports. 10: 3420 DOI: 10.1038/s41598-020-60179-z

Borgogna JC, Shardell MD, Santori EK, Nelson TM, Rath JM, Glover ED, Ravel J, Gravitt P, Yeoman CJ, Brotman RM. 2020. The vaginal metabolome and microbiota of cervical HPV-positive and HPV-negative women: a cross-sectional analysis. British Journal of Obstetrics & Gynecology. In press. DOI: 10.1111/1471-0528.15981

Nelson TM, Borgogna JC, Michalek, RD, Roberts DW, Rath JM, Glover ED, Ravel J, Shardell MD, Yeoman CJ, Brotman RM. 2018. Cigarette smoking is associated with an altered vaginal tract metabolomic profile. Scientific Reports. 8: 852. PubMed PMID: 29339821; PubMed Central PMCID: PMC5770521; DOI:10.1038/s41598-017-14943-3

Borgogna JC, Yeoman CJ. 2017. The Application of Molecular Methods to Improving Our Understanding of the Vaginal Microbiomes Role in Health and Disease. In: Methods in Microbiology (book chapter). Ed. Colin Harwood. Elsevier. 44: 37 – 91. DOI: 10.1016/bs.mim.2017.08.003

Nelson TM, Borgogna JL, Brotman RM, Ravel J, Walk ST, Yeoman CJ. 2015. Vaginal biogenic amines: Biomarkers of bacterial vaginosis or precursors to vaginal dysbiosis? Front. Physiol. 6:253. DOI: 10.3389/fphys.2015.00253

Avia Simmons PhD Candidate (2023 – )

Avia is studying the prevalence of Chlamydia in sheep throughout Montana and their impact on reproductive success.

Lab Alumni

Dr Tiffanie Nelson – NIH Postdoctoral Research Fellow (2014 – 2016)

Tiff is currently a Associate Research Fellow at the Geelong Center for Emerging Infectious Diseases. Keep up with Tiff’s research at Research Gate, Google Citations, and LinkedIn. Tiff can also be contacted at tiffanie.nelson@gmail.com

Tiff’s Publications with the Yeoman Lab.

Nelson TM, Borgogna JC, Michalek, RD, Roberts DW, Rath JM, Glover ED, Ravel J, Shardell MD, Yeoman CJ, Brotman RM. 2018. Cigarette smoking is associated with an altered vaginal tract metabolomic profile. Scientific Reports. 8: 85

Dr Suzanne Ishaq – Postdoctoral Research Fellow (2015 – 2017)

Sue is currently an Assistant Professor at U. Maine. Keep up with Sue’s research on her personal and professional web pages and at Research Gate, LinkedIn, and Google Citation. Sue also runs a science BLOG ‘Give Me The Short Version’. Sue can be contacted at sue.ishaq@maine.edu

Sue’s Publications with the Yeoman Lab.

Betiku OC, Yeoman CJ, Gaylord TG, Ishaq SL, Duff GC, Sealey WM. 2023. Evidence of a divided nutritive function in rainbow trout midgut and hindgut microbiomes by whole shotgun metagenomic approach. Aquaculture Reports. 30: 101601. DOI: 10.1016/j.aqrep.2023.101601

Dankwa AS, Humagain U, Ishaq SL, Yeoman CJ, Clark S, Beitz DC, Testroet ED. 2021. Bacterial communities in the rumen and feces of lactating Holstein dairy cows are not affected when fed reduced-fat dried distillers’ grains with solubles. Animal. 15: 100281. DOI: 10.1016/j.animal.2021.100281

Ishaq SL, Seipel T, Yeoman CJ, Menalled F. 2020. Dryland cropping systems, weed communities, and disease status modulate the effect of climate conditions on wheat soil bacterial communities. mSphere. 5:e00340-20 DOI: 10.1128/mSphere.00340-20

Ishaq SL, Seipel T, Yeoman CJ, Menalled FD. 2020. Soil bacterial communities of wheat vary across the growing season and among dryland farming systems. Geoderma. 358: 113989

Ishaq SL, Lachman MM, Wenner BA, Baeza A, Butler M, Gates E, Olivo S, Geddes JB, Hatfield P, Yeoman CJ. 2019. Pelleted-hay alfalfa feed increases sheep wether weight gain and rumen bacterial richness over loose-hay alfalfa feed. PLoS One 14: e0215797. DOI: 10.1371/journal.pone.0215797

Ishaq SL, Page CM, Yeoman CJ, Murphy TW, Van Emon ML, Stewart WC. 2019. Zinc-amino-acid supplementation alters yearling ram rumen bacterial communities but zinc sulfate supplementation does not. Journal of Animal Sciences. 97: 687 – 697. DOI: 10.1093/jas/sky456.

Yeoman CJ, Ishaq SL, Bichi E, Olivo SK, Lowe JL, Aldridge BM. 2018. Biogeographical differences in the influence of maternal microbial sources on the early successional development of the bovine neonatal gastrointestinal tract. Scientific Reports. 8: 3197. DOI:10.1038/s41598-018-21440-8

Ishaq SL, Yeoman CJ, Whitney TR. 2017. Ground redberry juniper and urea in supplements fed to Rambouillet ewe lambs. Part 2: Ewe lamb rumen microbial communities. Journal of Animal Sciences. 95: 4587. doi:10.2527/jas2017.1731

Perea K, Perz K, Olivo SK, Williams A, Lachman M, Ishaq SL, Thomson J, Yeoman CJ. 2017. Feed efficiency phenotypes in lambs involve changes in ruminal, colonic, and small intestine-located microbiota. Journal of Animal Sciences. 95(6):2585-2592. doi: 10.2527/jas.2016.1222

Ishaq SL, Johnson SP, Miller ZJ, Lehnhoff EA, Olivo S, Yeoman CJ, Menalled FD. 2017. Impact of cropping systems, soil inoculum, and plant species identity on soil bacterial community structure. Microbial Ecology 73(2): 417-434. doi: 10.1007/s00248-016-0861-2.

Feng W, Minor D, Liu M, Li J, Ishaq SL, Yeoman CJ, Lei B. 2016. Null mutations of group A Streptococcus orphan kinase RocA: Selection in mouse infection and comparison with CovS mutations in alteration of in vitro and in vivo protease SpeB expression and virulence. Infection and Immunity 85: e00790-16. doi: 10.1128/IAI.00790-16

Dr. Omolola Betiku – Animal Sciences Ph.D. (2013 – 2017)

Omolola Betiku (Lola) was the Yeoman lab’s first Ph.D. Her research sought to determine how diet and environment influence the gut microbiota of rainbow trout. Lola is now an Assistant professor at Florida A&M U. and can be contacted at ocbetiku@gmail.com

Lola’s Publications with the Yeoman Lab.

Betiku OC, Yeoman CJ, Gaylord TG, Duff GC, Hamerly T, Bothner B, Block SS, Sealey WM. 2017. Differences in Amino Acid Catabolism by Gut Microbes with/without Prebiotics Inclusion in GDDY-based Diet Affect Feed Utilization in Rainbow Trout. Aquaculture. In press

Betiku OC, Yeoman CJ, Gaylord TG, Americus B, Olivo S, Duff GC, Sealey W. 2018. Water system is a controlling variable modulating bacterial diversity of gastrointestinal tract and performance in Rainbow trout. PLoS One. 13: e0195967. DOI: doi.org/10.1371/journal.pone.0195967

Dr. Laura Brutscher Microbiology Ph.D. (2013 – 2017)

laura_headshot Laura applied molecular biology-based approaches to identify and investigate the endosymbiotic relationship between the Wheat Stem Sawfly. Laura can be contacted at laura.brutscher2@gmail.com

Laura’s Publication with the Yeoman Lab.

Yeoman CJ, Brutscher LM, Esen Ö, İbaoğlu F, Fowler C, Eren AM, Wanner K, Weaver DK. 2019. Genome-resolved insights into a novel Spiroplasma symbiont of the Wheat Stem Sawfly (Cephus cinctus). PeerJ 7:e7548 DOI: 10.7717/peerj.7548

Savannah Grace – MS Animal Sciences (2020 – 2022)

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Savannah studied the microbiome of Montana’s wealth of wild ruminant populations and examined for microbial activities capable of degrading the potent Larkspur toxin Methyllycacontine (MLA) with the goal of identifying microbes that could be introduced to domestic cattle to protect them against larkspur toxicosis.

Savannah’s Publications with the Yeoman Lab.

Herlin (Eri) Kadriu – MS (professional) Microbiology (2020 – 2023)

[Picture to come] Eri developed organoid models of the beef cattle small intestine and uterus that are being used in various projects.

Eri’s Publications with the Yeoman Lab.

Kadriu H, Yeoman CJ. 2022. The unseen minority: Biogeographical investigations of the ruminant gastrointestinal microbiome highlight the importance of frequently ignored regions. In: Kogut MH & Zhang G. (Eds.), Gut Microbiota, Immunity, and Health in Production Animals. The Microbiomes of Humans, Animals, Plants, and the Environment, vol 4. Springer, Cham. DOI: 10.1007/978-3-030-90303-9_9

Technical Staff

Sarah Olivo (2015 – 2017)

Julie Buono Geddes (2015), Laboratory Technician.

Thomas O’Neill (2013 – 2014) , Laboratory Technician.

Undergraduates

Kellie Corona (2023 -)

Bridget Dassenko (2023 – )

Chloe Henry (2023 -)

Katie Frederick (2023 -)

River Dauwen (2023 -)

Sean Boyd (2023) REU Fellow

Tadeo Aviles-Zuniga (2022) REU Fellow

Aiden McVey (2019)

Darien Kadriu (2019 – 2023) INBRE-USP Scholar

Herlin Kadriu (2018 – 2020) INBRE-USP Scholar

Daria Kotov (2018)

Savannah Gray (2018 – 2019)

Deanna Desonn (2017 – 2018)

Dusti East (2017)

Amanda Embleton (2016 – 2017)

Jessica Donahoo (2016 – 2017)

Trent Jones (2016 – 2017)

Elisa Santori (2016 – 2017) INBRE-USP Scholar

Katheryn Parea (Summer 2016), INBRE Fellow

Megan Meyer (2016)

Curtis Fowler (2015-2016), Undergraduate Researcher

Benjamin Americus (2015-2016), Undergraduate Researcher

Amy Baeza (2014)

Kiki Potter-Jacobs (2014 – 2015)

Jessica Eggers (Summer 2014), Bozeman High School Research Intern.

Tasia Hvamstad (Summer 2014), Montana Apprenticeship Program Research Intern.

Raven Warner (Summer 2014), Montana Apprenticeship Program Research Intern

Medora Lachman (2014 – 2017).

Niall Clancy (2014) Undergraduate Intern

Josh Failing (Summer 2013), Montana Apprenticeship Program Research Intern.

Courtney Subatch (Summer 2013), Montana Apprenticeship Program Research Intern.

Kesley Westveer (Spring 2013), Biotechnology Intern.

Jillian Hatfield (Fall 2012), Undergrad Intern.

Emme Troendle, Research Intern.